abstract：:Although stress simultaneously affects and causes changes in central nervous system systems together with the sympathetic nervous system and the hypothalamus-pituitary-adrenal axis, this interaction and its behavioral consequences are rarely assessed. The current paper first describes the different systems involved in...

journal_title：Psychoneuroendocrinology

authors： Andrews J,Ali N,Pruessner JC

更新日期：2013-07-01 00:00:00

abstract：:It is widely assumed that learning and memory processes play an important role in the pathogenesis, expression, maintenance and therapy of anxiety disorders, such as phobias or post-traumatic stress disorder (PTSD). Memory retrieval is involved in symptom expression and maintenance of these disorders, while memory ext...

journal_title：Psychoneuroendocrinology

authors： Bentz D,Michael T,Wilhelm FH,Hartmann FR,Kunz S,von Rohr IR,de Quervain DJ

更新日期：2013-07-01 00:00:00

abstract：:In the laboratory, prenatal stress produces alterations in the structure and function of corticolimbic neurons. Here we report changes in gene expression and corticolimbic dendritic spine morphology in the offspring of pregnant ewes subjected to aversive interactions with human handlers during the last five weeks of p...

journal_title：Psychoneuroendocrinology

authors： Coulon M,Wellman CL,Marjara IS,Janczak AM,Zanella AJ

更新日期：2013-07-01 00:00:00

abstract：:Brain oxytocin (OXT) plays an important role in short-term social memory in laboratory rodents. Here we monitored local release of OXT and its functional involvement in the maintenance and retrieval of social memory during the social discrimination test. We further assessed, if the local effects of OXT within the medi...

journal_title：Psychoneuroendocrinology

authors： Lukas M,Toth I,Veenema AH,Neumann ID

更新日期：2013-06-01 00:00:00

abstract：:Distinct patterns of cortisol secretion have been associated with depression in past research, but it remains unclear whether individuals at-risk for depression may also have similar patterns of cortisol secretion. This is the first study to date of both naturalistic diurnal cortisol secretion and cortisol reactivity ...

journal_title：Psychoneuroendocrinology

authors： Dienes KA,Hazel NA,Hammen CL

更新日期：2013-06-01 00:00:00

abstract：CONTEXT:The rise of cortisol concentrations after awakening is well documented in adults and children and commonly used as easily accessible marker of hypothalamic-pituitary-adrenal (HPA) reactivity. OBJECTIVE:The purpose of this study was to demonstrate the existence of a salivary cortisol awakening response (CAR) in...

journal_title：Psychoneuroendocrinology

authors： Tegethoff M,Knierzinger N,Meyer AH,Meinlschmidt G

更新日期：2013-05-01 00:00:00

abstract：:Previous studies with prairie voles suggest that the hormone oxytocin is crucial for bond formation - indicated when a partner preference is formed towards the target vole. In this study, we conduct the first empirical test of whether oxytocin likewise promotes partner preferences in humans. Seventy-six undergraduate ...

journal_title：Psychoneuroendocrinology

authors： Liu JC,Guastella AJ,Dadds MR

更新日期：2013-04-01 00:00:00

abstract：:The current study investigated the associations between thyroid stimulating hormone (TSH), free thyroxine (T(4)) and cognitive ability (general ability, memory and processing speed), in a large age homogenous sample (n=659) of generally healthy euthyroid older adults. Associations were considered both at baseline (mea...

journal_title：Psychoneuroendocrinology

authors： Booth T,Deary IJ,Starr JM

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:In chronic sexual abuse victims with post traumatic stress disorder (PTSD), the hypothalamic pituitary adrenal (HPA) axis can be dysregulated. In single rape victims, PTSD symptoms are hypothesized to function as a chronic stressor leading to similar HPA-axis dysregulation. The objective of the current study...

journal_title：Psychoneuroendocrinology

authors： Bicanic IA,Postma RM,Sinnema G,De Roos C,Olff M,Van Wesel F,Van de Putte EM

更新日期：2013-03-01 00:00:00

abstract：:This study examined the relationship between children's hair cortisol and socioeconomic status of the family, as measured by parental education and income. Low family socioeconomic status has traditionally been considered a long-term environmental stressor. Measurement of hair cortisol provides an integrated index of ...

journal_title：Psychoneuroendocrinology

authors： Vaghri Z,Guhn M,Weinberg J,Grunau RE,Yu W,Hertzman C

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:The S'/S' (S/S, S/Lg and Lg/Lg) variant of the serotonin (5-HT) transporter gene linked polymorphic region (5-HTTLPR) is associated with less efficient neurotransmission and may be more reactive to 5-HT manipulations. We tested the effects of l-tryptophan supplements on the cortisol response induced by a soci...

journal_title：Psychoneuroendocrinology

authors： Cerit H,Jans LA,Van der Does W

更新日期：2013-02-01 00:00:00

abstract：:Psychiatric disorders associated with elevated stress levels, such as depression, are present in many epilepsy patients, including those with mesial Temporal Lobe Epilepsy (mTLE). Evidence suggests that these psychiatric disorders can predate the onset of epilepsy, suggesting a causal/contributory role. Prolonged expo...

journal_title：Psychoneuroendocrinology

authors： Jones NC,Lee HE,Yang M,Rees SM,Morris MJ,O'Brien TJ,Salzberg MR

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Nightmares and insomnia in PTSD are hallmark symptoms, yet poorly understood in comparison to the advances toward a biological framework for the disorder. According to polysomnography (PSG), only minor changes in sleep architecture were described. This warrants alternative methods for assessing sleep regulat...

journal_title：Psychoneuroendocrinology

authors： van Liempt S,Arends J,Cluitmans PJ,Westenberg HG,Kahn RS,Vermetten E

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Flibanserin, a novel serotonin (5-HT)(1A) agonist and 5-HT(2A) antagonist, has been shown to increase sexual desire and reduce distress in women with Hypoactive Sexual Desire Disorder (HSDD). In marmoset monkeys, flibanserin has demonstrated pro-social effects on male-female pairmates, while the classic 5-HT...

journal_title：Psychoneuroendocrinology

authors： Aubert Y,Bohl MA,Lange JR,Diol NR,Allers KA,Sommer B,Datson NA,Abbott DH

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Individuals who are exposed to a traumatic event are at increased risk of developing psychiatric disorders such as posttraumatic stress disorder (PTSD). Studies have shown that increased amygdala activity is frequently found in patients with PTSD. In addition, pre-trauma glucocorticoid receptor (GR) number...

journal_title：Psychoneuroendocrinology

authors： Geuze E,van Wingen GA,van Zuiden M,Rademaker AR,Vermetten E,Kavelaars A,Fernández G,Heijnen CJ

更新日期：2012-11-01 00:00:00

abstract：:The neuropeptide oxytocin (OT) is well known for its profound effects on social behavior, which appear to be mediated by an OT-dependent modulation of amygdala activity in the context of social stimuli. In humans, OT decreases amygdala reactivity to threatening faces in males, but enhances amygdala reactivity to simil...

journal_title：Psychoneuroendocrinology

authors： Lischke A,Gamer M,Berger C,Grossmann A,Hauenstein K,Heinrichs M,Herpertz SC,Domes G

更新日期：2012-09-01 00:00:00

abstract：:There is now an expanding volume of evidence to support the view that commensal organisms within the gut play a role in early programming and later responsivity of the stress system. The gut is inhabited by 10¹³-10¹⁴ micro-organisms, which is ten times the number of cells in the human body and contains 150 times as ma...

journal_title：Psychoneuroendocrinology

authors： Dinan TG,Cryan JF

更新日期：2012-09-01 00:00:00

abstract：:Neurobehavioral symptoms are frequently reported in patients with diabetes. Nevertheless, the characterization of the specific symptom dimensions that develop in diabetic patients with respect to disease phenotype and treatment status remains obscure. This study comparatively assessed fatigue symptoms and cognitive pe...

journal_title：Psychoneuroendocrinology

authors： Lasselin J,Layé S,Barreau JB,Rivet A,Dulucq MJ,Gin H,Capuron L

更新日期：2012-09-01 00:00:00

abstract：:Accumulating evidence suggests that there is a rich cross-talk between the neuroimmune system and neuroplasticity mechanisms under both physiological conditions and pathophysiological conditions in depression. Anti-neuroplastic changes which occur in depression include a decrease in proliferation of neural stem cells ...

journal_title：Psychoneuroendocrinology

authors： Eyre H,Baune BT

更新日期：2012-09-01 00:00:00

abstract：INTRODUCTION:Childhood sexual abuse (CSA) has been associated with dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in non-pregnant samples. However, it is not yet known whether CSA is associated with HPA dysregulation over pregnancy. In the present study we assessed whether maternal cortisol levels acros...

journal_title：Psychoneuroendocrinology

authors： Bublitz MH,Stroud LR

更新日期：2012-09-01 00:00:00

abstract：:Recent studies have demonstrated alterations in the cortisol awakening response (CAR) and brain abnormalities in adults with obesity and type 2 diabetes mellitus (T2DM). While adolescents with T2DM exhibit similar brain abnormalities, less is known about whether brain impairments and hypothalamic-pituitary-adrenal (HP...

journal_title：Psychoneuroendocrinology

authors： Ursache A,Wedin W,Tirsi A,Convit A

更新日期：2012-08-01 00:00:00

abstract：:Females begin to demonstrate greater negative affective responses to stress than males in adolescence. This may reflect the concurrent emergence of underlying differences in physiological response systems, including corticolimbic circuitries, the hypothalamic-pituitary-adrenal axis (HPAA), and the autonomic nervous sy...

journal_title：Psychoneuroendocrinology

authors： Ordaz S,Luna B

更新日期：2012-08-01 00:00:00

abstract：:Hormone reactivity to stressors and hormones that rapidly change at puberty are hypothesized to influence moods, which may in turn affect parent-child relationship quality. The present study investigated whether reactivity of testosterone, DHEA, and cortisol in a clinic setting (venipuncture paradigm) predicted negati...

journal_title：Psychoneuroendocrinology

authors： Marceau K,Dorn LD,Susman EJ

更新日期：2012-08-01 00:00:00

abstract：:In today's increasingly interconnected world, deciding with whom and at what level to cooperate becomes a matter of increasing importance as societies become more globalized and large-scale cooperation becomes a viable means of addressing global issues. This tension can play out via competition between local (e.g. wit...

journal_title：Psychoneuroendocrinology

authors： Israel S,Weisel O,Ebstein RP,Bornstein G

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Stress reducing effects of Taiji, a mindful and gentle form of body movement, have been reported in previous studies, but standardized and controlled experimental studies are scarce. The present study investigates the effect of regular Taiji practice on psychobiological stress response in healthy men and wom...

journal_title：Psychoneuroendocrinology

authors： Nedeljkovic M,Ausfeld-Hafter B,Streitberger K,Seiler R,Wirtz PH

更新日期：2012-08-01 00:00:00

abstract：:The acute phase response to infection is reliably accompanied by decreases in social investigation; however, social behavior is commonly assayed in inescapable environments using unfamiliar social stimuli. In this experiment, male Wistar rats were raised from weaning with 2 familiar, same-sex conspecifics. In adulthoo...

journal_title：Psychoneuroendocrinology

authors： Yee JR,Prendergast BJ

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Serotonin influences the development of the hypothalamic-pituitary-adrenal (HPA) system; therefore prenatal exposure to selective serotonin reuptake inhibitor antidepressants (SSRIs) may alter HPA axis development and function. To address this, prenatal exposure to SSRIs and maternal mood were examined in re...

journal_title：Psychoneuroendocrinology

authors： Pawluski JL,Brain UM,Underhill CM,Hammond GL,Oberlander TF

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Hypothalamic-pituitary-adrenal (HPA)-axis hyperactivity has been observed in (recurrent) major depressive disorder (MDD), although inconsistently and mainly cross-sectional. Longitudinal studies clarifying state-trait issues are lacking. We aimed to determine whether HPA-axis (hyper)activity in recurrent MDD...

journal_title：Psychoneuroendocrinology

authors： Lok A,Mocking RJ,Ruhé HG,Visser I,Koeter MW,Assies J,Bockting CL,Olff M,Schene AH

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Raised maternal anxiety during pregnancy is associated with increased risk of adverse neurodevelopmental outcomes for her child. The mechanisms underlying this are not known but animal studies suggest prenatal stress may alter the function of the placenta. Here we determined whether maternal prenatal anxiety...

journal_title：Psychoneuroendocrinology

authors： O'Donnell KJ,Bugge Jensen A,Freeman L,Khalife N,O'Connor TG,Glover V

更新日期：2012-06-01 00:00:00

abstract：:Pain and fatigue have been identified as core symptoms of fibromyalgia syndrome (FMS). Since both symptoms are also characteristic of hypocortisolemic disorders, reduced cortisol levels have been thought to promote an exacerbation of these FMS core symptoms by an enhanced reactivity of interleukin-6 (IL-6) levels. The...

journal_title：Psychoneuroendocrinology

authors： Geiss A,Rohleder N,Anton F

更新日期：2012-05-01 00:00:00

abstract：:Data from animal studies suggest that oxytocin is an important modulating neuropeptide in regulation of social interaction. One human study has reported a negative correlation between CSF oxytocin levels, life history of aggression and suicidal behaviour. We hypothesized that CSF oxytocin levels would be related to su...

journal_title：Psychoneuroendocrinology

authors： Jokinen J,Chatzittofis A,Hellström C,Nordström P,Uvnäs-Moberg K,Asberg M

更新日期：2012-04-01 00:00:00

abstract：:Many sex differences can be found in the expression of aggression and parental nurturing behaviors. It is important to determine if these are modulated by prenatal conditions. Here, using assisted reproduction technologies, we generated females that were (mixed-sex) or were not (same-sex) exposed to males during fetal...

journal_title：Psychoneuroendocrinology

authors： Sugawara A,Pearson BL,Blanchard DC,Ward MA

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:The renin-angiotensin-aldosterone-system (RAAS) is one of the most important systems involved in the pathogenesis of cardiovascular diseases. Its role in stress response has been generally neglected, although the progression of cardiovascular disease is considerably increased in the presence of stress and ...

journal_title：Psychoneuroendocrinology

authors： Häfner S,Baumert J,Emeny RT,Lacruz ME,Bidlingmaier M,Reincke M,Kuenzel H,Holle R,Rupprecht R,Ladwig KH,MONICA\/KORA Study Investigators.

更新日期：2012-02-01 00:00:00

abstract：:Since hypnosis was popularly recognized in the nineteenth century, the phenomenon of hypnotizability has remained poorly understood. The capacity to increase hypnotizability has important implications because it may increase the number of people who can benefit from hypnotic interventions for psychological and medical...

journal_title：Psychoneuroendocrinology

authors： Bryant RA,Hung L,Guastella AJ,Mitchell PB

更新日期：2012-01-01 00:00:00

abstract：:The Trier Social Stress Test (TSST) is an effective psychosocial laboratory protocol for inducing stress in humans and has been used in numerous research studies. The stressor leads to a physiological response of the hypothalamus-pituitary-adrenal axis (HPAA) and the autonomous nervous system (ANS). Common biomarkers ...

journal_title：Psychoneuroendocrinology

authors： Hellhammer J,Schubert M

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To investigate the neuroendocrinological stress response to acute psychosocial stress in a clinical sample of female adolescents engaging in nonsuicidal self-injury (NSSI). METHODS:The Trier Social Stress Test (TSST), a standardized psychosocial stress protocol, was performed in 14 female patients who engage...

journal_title：Psychoneuroendocrinology

authors： Kaess M,Hille M,Parzer P,Maser-Gluth C,Resch F,Brunner R

更新日期：2012-01-01 00:00:00

abstract：CONTEXT:Affective symptoms are poorly understood in polycystic ovary syndrome (PCOS). Clinical signs of hyperandrogenism and high serum androgens are key features in PCOS, and women with PCOS are more likely to be overweight or obese, as well as insulin resistant. Further, PCOS is associated with high sympathetic nerve...

journal_title：Psychoneuroendocrinology

authors： Jedel E,Gustafson D,Waern M,Sverrisdottir YB,Landén M,Janson PO,Labrie F,Ohlsson C,Stener-Victorin E

更新日期：2011-11-01 00:00:00

abstract：:Diabetes is a highly prevalent, chronic disease that requires ongoing, multi-specialty medical care combined with patient self-management, family support, and education to prevent or delay end-organ morbidity and mortality. There is clearly an increased prevalence of major depressive disorder, a relatively common and ...

journal_title：Psychoneuroendocrinology

authors： Rustad JK,Musselman DL,Nemeroff CB

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Healthy sleep facilitates the consolidation of newly acquired memories. Although patients with posttraumatic stress disorder (PTSD) often complain of sleep disturbances and memory deficits, the interrelatedness of these symptoms is not well understood. Sleep may be disturbed in PTSD by increased awakenings d...

journal_title：Psychoneuroendocrinology

authors： van Liempt S,Vermetten E,Lentjes E,Arends J,Westenberg H

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:There is increasing evidence indicating that slow wave sleep (SWS) supports memory consolidation. This effect may in part originate from phasic noradrinergic (NE) activity occurring during SWS in the presence of tonically lowered NE levels. Here, we examined whether NE supports the consolidation of amygdala-...

journal_title：Psychoneuroendocrinology

authors： Groch S,Wilhelm I,Diekelmann S,Sayk F,Gais S,Born J

更新日期：2011-10-01 00:00:00